The world is a complex system, and understanding it scientifically requires advanced computational resources and approaches. Engineers design the most powerful computers on Earth in order to model and simulate physical systems such as global climate, the expansion of the universe, and the behavior of matter at an atomic level. But today, high performance scientific computing means more than just supercomputers running numerical models, expanding to large-scale data analysis, AI and machine learning, visualization, and distributed and heterogeneous hardware systems.

UChicago CS researchers are changing the face of high performance computing (HPC), creating new computing paradigms at scale for understanding physical, biological, social, and ecological systems and answering the most significant questions facing society. Faculty lead efforts to apply the latest AI and data science approaches for scientific discovery, from computational imaging and spectroscopy to bioinformatics, neuroscience, and agriculture. In these areas, as well as in the development and application of new exascale systems such as Aurora, UChicago CS benefits from a strong partnership with Argonne National Laboratory.

Labs & Groups

Globus Labs

Ian Foster, Kyle Chard
Realizing a world in which all research data are reliably, rapidly, and securely accessible, discoverable, and usable.

Large-Scale Systems Group (LSSG)

Andrew A. Chien
Exploring critical systems research questions underlying sustainable, scalable large-scale systems, including cloud, high performance, edge, and mobile/IoT computing.


Kate Keahey, Haryadi Gunawi
A configurable experimental environment for large-scale edge to cloud research.

Center for Translational Data Science

Robert Grossman
A research center developing the discipline of translational data science and applying to advance biology, medicine, healthcare and environmental research.

Related Faculty

Kyle Chard

Research Associate Professor of Computer Science

Andrew A. Chien

William Eckhardt Distinguished Service Professor of Computer Science

Anshu Dubey

Senior Scientist, CASE Affiliate

Todd Dupont

Professor Emeritus of Computer Science, Mathematics, and the James Franck Institute

Ian Foster

Arthur Holly Compton Distinguished Service Professor of Computer Science

Robert Grossman

Frederick H. Rawson Distinguished Service Professor in Medicine, Computer Science

Rana Hanocka

Assistant Professor of Computer Science

Kate Keahey

Senior Scientist, CASE Affiliate

Gordon Kindlmann

Associate Professor of Computer Science

Rick Stevens

Professor of Computer Science

Rebecca Willett

Professor of Computer Science, Statistics

News & Events

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Alumni Spotlight: Dixin Tang, Assistant Professor of Computer Science at UT Austin

Feb 05, 2024
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NetMicroscope Uses AI to Improve Network Monitoring for a Better Internet Experience

Feb 01, 2024
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NeurIPS 2023 Award-winning paper by DSI Faculty Bo Li, DecodingTrust, provides a comprehensive framework for assessing trustworthiness of GPT models

Feb 01, 2024
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New research unites quantum engineering and artificial intelligence

Jan 29, 2024

“Machine Learning Foundations Accelerate Innovation and Promote Trustworthiness” by Rebecca Willett

Jan 26, 2024

Nightshade: Data Poisoning to Fight Generative AI with Ben Zhao

Jan 23, 2024
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Exploring 3D Paintbrush: An AI That Colors with Words

Jan 22, 2024
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Group From UChicago CS To Present Four Papers at Most Prestigious International Quantum Conference

Jan 09, 2024
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Alumni Spotlight: Get To Know Emily Wenger, a 2023 CS Graduate Who Was Just Named To The Forbes 30 Under 30 List

Nov 29, 2023
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Three UChicago PhD Students From The Department of Computer Science Named To Forbes 30 Under 30 List

Nov 28, 2023
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High School Students In The Collegiate Scholars Program Get To Know Robots

Nov 14, 2023
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AxLab Features Multidisciplinary Works at World’s Largest Art and Technology Festival

Nov 03, 2023
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