The world is a complex system, and understanding it scientifically requires advanced computational resources and approaches. Engineers design the most powerful computers on Earth in order to model and simulate physical systems such as global climate, the expansion of the universe, and the behavior of matter at an atomic level. But today, high performance scientific computing means more than just supercomputers running numerical models, expanding to large-scale data analysis, AI and machine learning, visualization, and distributed and heterogeneous hardware systems.

UChicago CS researchers are changing the face of high performance computing (HPC), creating new computing paradigms at scale for understanding physical, biological, social, and ecological systems and answering the most significant questions facing society. Faculty lead efforts to apply the latest AI and data science approaches for scientific discovery, from computational imaging and spectroscopy to bioinformatics, neuroscience, and agriculture. In these areas, as well as in the development and application of new exascale systems such as Aurora, UChicago CS benefits from a strong partnership with Argonne National Laboratory.

Labs & Groups

Globus Labs

Ian Foster, Kyle Chard
Realizing a world in which all research data are reliably, rapidly, and securely accessible, discoverable, and usable.

Large-Scale Systems Group (LSSG)

Andrew A. Chien
Exploring critical systems research questions underlying sustainable, scalable large-scale systems, including cloud, high performance, edge, and mobile/IoT computing.


Kate Keahey, Haryadi Gunawi
A configurable experimental environment for large-scale edge to cloud research.

Center for Translational Data Science

Robert Grossman
A research center developing the discipline of translational data science and applying to advance biology, medicine, healthcare and environmental research.

Related Faculty

Kyle Chard

Research Associate Professor

Andrew A. Chien

William Eckhardt Distinguished Service Professor, Department of Computer Science

Anshu Dubey

Senior Scientist, CASE Affiliate

Todd Dupont

Professor, Departments of Computer Science and Mathematics and the James Franck Institute

Ian Foster

Arthur Holly Compton Distinguished Service Professor, Department of Computer Science

Robert Grossman

Frederick H. Rawson Distinguished Service Professor in Medicine and Computer Science

Rana Hanocka

Assistant Professor, Department of Computer Science, College

Eric Jonas

Assistant Professor, Department of Computer Science

Kate Keahey

Senior Scientist, CASE Affiliate

Gordon Kindlmann

Associate Professor, Department of Computer Science

Rick Stevens

Professor, Department of Computer Science

Rebecca Willett

Professor, Departments of Computer Science and Statistics

News & Events

Past Event

Three-Minute Madness!

Oct 12, 2022
UChicago CS News

UChicago Leads New Research Coordination Network for Promoting CS Reproducibility

Sep 16, 2022
UChicago CS News

UChicago/Argonne Computer Scientist Ian Foster Receives ACM/IEEE Ken Kennedy Award

Sep 07, 2022
UChicago CS News

UChicago/Argonne Researchers Will Cultivate AI Model “Gardens” With $3.5M NSF Grant

Aug 30, 2022
Past Event

DSI Summer Lab: Final Symposium

Aug 19, 2022
UChicago CS News

EPiQC Post-Doc Pens Op-Ed on Potential of Quantum Computing for Chemistry

Jun 24, 2022
UChicago CS News

Two Incoming UChicago CS PhD Students Receive Department of Energy Fellowship

Jun 16, 2022
UChicago CS News

DSI Summer Lab Returns In-Person With 49 Students From Across the U.S.

Jun 14, 2022
In the News

Chameleon Cloud Testbed Hosts HPC Competition, Gains New Associates and Users

Mar 14, 2022
UChicago CS News

$3.25m DOE Grant Funds UChicago/Argonne Research on AI Models of Physics Simulations

Sep 27, 2021
UChicago CS News

Scientists Use Artificial Intelligence to Detect Gravitational Waves

Jul 16, 2021
UChicago CS News Digital Transformation Institute Announces CFP to Advance AI for Energy and Climate Security

Feb 02, 2021
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